How much is a ticket from Chicago O'Hare to Santa Cruz de la Sierra?

Flight prices from Chicago to Santa Cruz change depending on demand and time of booking.

Select your dates to check current offers.

Flying at off-peak hours — such as early morning or late evening — can help you save. Also, the best deals tend to appear in the weeks leading up to departure.

Flying between Chicago and Santa Cruz? Consider these airports

Depending on your destination and where you’re starting from, it might make sense to look beyond the main hubs.

• Airports in Chicago: Chicago has 3 airports - Midway, O'Hare, Rockford.
• Airports in Santa Cruz: Besides Santa Cruz - Viru Viru, also consider Santa Cruz.

Check if your destination airport has a rail link — it can make getting around easier. Jetcost lets you view options from all Chicago airports in a single search.

Find flights from Chicago O'Hare to Santa Cruz de la Sierra that suit your schedule

Use Jetcost to sort and filter results based on your preferred flight time, number of stops, price range, or airline. View deals from Ryanair, British Airways, Easyjet, and booking sites like Expedia and eDreams.

Other popular destinations

Interested in Bolivia? These cities are also in demand: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

Connecting flights can be cheaper but often mean longer layovers. You can easily select either direct or connecting flights with a single click using the filters.