Flight prices from San Francisco to Mytilene

There’s no fixed price — fares between San Francisco and Mytilene can vary a lot by day or time.

Choose a date to explore the best fares now.

The lowest fares are often found with some flexibility in travel dates. If your plans are flexible, you’ll have a better chance of finding cheap flights.

Is there more than one airport in San Francisco or Mytilene?

Even short-haul routes can benefit from considering secondary airports. It may open up more flight times or cheaper fares.

• Airports in San Francisco: Only San Francisco is currently operational.
• Airports in Mytilene: Mytilene is the only airport in operation.

Airports with more daily flights offer more flexibility if plans change or delays occur. If you’re flexible, consider airports near Mytilene as well.

Customize your flight from San Francisco to Mytilene

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from Ryanair, Easyjet, British Airways, Expedia, eDreams, and more.

Other popular destinations

Thinking about Greece? You might also consider: Athens, Crete, Kerkyra, Thessaloniki, Thira.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.