What’s the cost of a flight from Santo Domingo to Guayaquil?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Santo Domingo and Guayaquil.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

Flying between Santo Domingo and Guayaquil? Consider these airports

Depending on your destination and where you’re starting from, it might make sense to look beyond the main hubs.

• Airports in Santo Domingo: Santo Domingo has only one airport in service, Santo Domingo - Mayo Guerrero.
• Airports in Guayaquil: The only active option is Guayaquil.

Check if your destination airport has a rail link — it can make getting around easier. Jetcost lets you view options from all Santo Domingo airports in a single search.

Plan your perfect flight from Santo Domingo to Guayaquil

Jetcost gives you full control over your flight search. Filter by date, time, duration, price, and airline. See round-trip and one-way options from low-cost and full-service carriers like Ryanair, British Airways, Easyjet, and more.

Other popular destinations

Planning a trip to Ecuador? Other frequent searches include: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

Some airlines include baggage in the fare, others don’t — always check the details before booking. If you're looking for round-trip flights, you can easily see the most convenient combinations.